With Christian McCaffrey ruled out for the remainder of the game with a knee injury, the San Francisco 49ers run game went through Jordan Mason and rookie Isaac Guerendo on Sunday Night Football against the Buffalo Bills.
With the 49ers trailing 28-3 in the second half, Guerendo helped get the 49ers on the board with a touchdown late in the third quarter. The rookie running back out of Louisville broke around the left side of the field for a 15-yard touchdown run.
Via @SNFonNBC on Twitter:
Guerendo's touchdown on Sunday marked the second touchdown of his rookie campaign. Guerendo has rushed the ball 38 times for 227 during his rookie season with the 49ers.
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